Benji
Can't help you about selling the collection as a whole and ebay is painstaking but gets you there in the end. You could try selling in lots and there are a lot of collectors out there looking not only for specific clubs but also one-per-club-per-season, big games, European competition, cup-ties etc.
There are also a lot of Facebook and Twitter pages dedicated to Programmes and Ticket collectors where buy, sell and trade goes on. If you use these platforms they're easy to find. Doesn't have the security of eBay and lots of ******s out there, but it has its advantages as there are no seller fees or Paypal fees if the buyer is willing to use Friends & Family as payment method.

I have a few Hibs wants amongst:
Home Postponements.
1950-60 friendlies home and away.
Away friendlies v non league clubs.
European aways.
Some single domestic aways 1960 - 1980.
Some Championship run aways 1998-99.

PM me if you have any lists, i'd like to hear from you or I can send you my needs! I'll pay the fair price, cash if you are local, even though I'm sorry you're selling.